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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2026-06-11 23:58 |
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Conference: Bucharest University Faculty of Physics 2026 Meeting
Section: Biophysics; Medical Physics
Title:
Multifunctional Phyto-Based Biohybrids with Biomedical Potential
Authors:
D.-M. FLOREA (1), G.-A. GRIGORE (2,3), Adrian BOBICĂ (4), C. NICHITA (3,5,6), M.-E. BARBINTA-PATRASCU (1)
*
Affiliation:
(1) University of Bucharest, Faculty of Physics, Department of Electricity, Solid-State Physics and Biophysics, 405 Atomistilor Street, PO Box MG-11, 077125 Magurele, Ilfov, Romania
(2) University of Bucharest, Faculty of Biology, Splaiul Independentei 91-95, 050095 Bucharest, Romania
(3) Research Institute of the University of Bucharest—ICUB, University of Bucharest, 050663 Bucharest, Romania
(4) CROMATEC PLUS SRL, 1 Petre Ispirescu Street, Tâncăbeşti, 077167, Ilfov, Romania
(5) University of Bucharest, Faculty of Physics, ICUB, CTT 3Nano-SAE Research Center, MG-38, 405 Atomistilor Street, 077125, Magurele, Romania
(6) National Institute for Chemical – Pharmaceutical Research and Development, 112 Vitan Avenue, 031299, Bucharest, Romania
E-mail
daria.maria.florea29@gmail.com, marcela.barbinta@unibuc.ro
Keywords:
phyto-vesicles, "green" silver nanoparticles, antibacterial biohybrids
Abstract:
Development of nanostructured biohybrid systems represents an important direction in current biomedical research due to their ability to combine the properties of natural bioactive compounds with the advantages of nanomaterials. The present study aimed to obtain and characterize multifunctional phyto-based biohybrids using phyto-vesicles and "green" silver nanoparticles (AgNPs), in order to evaluate their biomedical potential. AgNPs were prepared through green synthesis, using aqueous vegetal extract. The developed biohybrids were characterized by various spectral methods (UV–Vis absorption, fluorescence emission, and FTIR-ATR spectroscopy). The obtained phyto-based structures presented antioxidant activity, and also antibacterial activity against Enterococcus faecalis.
References:
1) Barbinta-Patrascu, M.-E.; Nichita, C.; Enculescu, M.; Maraloiu, V.-A.; Bacalum, M.; Ungureanu, C.; Negrila, C.C.; Zgura, I. Bioactive Hybrids Containing Artificial Cell Membranes and Phyto-Gold–Silver Chloride Bio-Nanoparticles. Int. J. Mol. Sci. 2024, 25, 11929. https://doi.org/10.3390/ijms252211929
2) M.-E. Barbinta-Patrascu, N. Badea, C. Pirvu, M. Bacalum, C. Ungureanu, P.L. Nadejde, C. Ion, I. Rau, Multifunctional soft hybrid bio-platforms based on nano-silver and natural compounds, Mat. Sci. Eng. C, 69, 922-932, 2016. doi:10.1016/j.msec.2016.07.077
Acknowledgement:
This work was supported by a grant of the Ministry of Education and Research, CCCDI -UEFISCDI, project number PN-IV-P7-7.1-PED-2024-0690, within PNCDI IV [31PED⁄2025, Eco-innovative novel phyto-derived 3D hybrid bioarchitectures for a better life (ECOPHYTO)]. This work was also supported by the Culture Collection of Microorganisms of Industrial Importance (CMII-ICCF-WFCC 232, MIRRI-RO).
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